Electrochemical ion gradients and the Na/Ca exchange stoichiometry. Measurements of these gradients are thermodynamically consistent with a stoichiometric coefficient greater than or equal to 3.

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Electrochemical ion gradients and the Na/Ca exchange stoichiometry. Measurements of these gradients are thermodynamically consistent with a stoichiometric coefficient greater than or equal to 3

Dear Sir: With ion-selective microelectrodes, it is possible to measure intracellular ion activities and calculate transmembrane electrochemical potential differences. Recently, these techniques have been carefully applied to the measurement of Na and Ca ion activities in mammalian ventricular and Purkinje fibers (Sheu and Fozzard, 1982). The results show that under a wide variety of circumstan...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1985

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.85.3.471